REACT study shows COVID-19 infection rates three times lower for double vaccinated people

REACT study shows COVID-19 infection rates three times lower for double vaccinated people

Interim findings from the latest report of REACT-1, one of the country’s largest studies into COVID-19 infections in England, have been published by Imperial College London and Ipsos MORI.

Over 47,000 volunteers returned PCR tests in England between 24 June and 5 July to examine the levels of COVID-19 in the general population. The latest data show infections in England have increased fourfold from 0.15% to 0.59% since the last REACT-1 report which covered 20 May to 7 June.

The main findings from the first half of the thirteenth round of the REACT-1 study show:

  • overall prevalence nationally is substantially higher in round 13 interim (swabs taken 24 June to 5 July) than round 12 (swabs taken 20 May to 7 June), rising from 0.15% to 0.59% – an approximately fourfold increase with around 1 in 170 people testing positive;
  • continued exponential growth in prevalence with an average doubling time of 15 days between round 12 (swabs taken 20 May – 7 June) and round 13;
  • however, during the first half of round 13 only, there was a doubling time of 6.1 days with a corresponding R value of 1.87;
  • there have been substantial increases in all age groups under the age of 75 years, and especially at younger ages, with the highest prevalence for 13 to 17 years at 1.33% and 18 to 24 years at 1.40%;
  • infections have increased in all regions with the largest increase in London, where prevalence has increased more than eightfold from 0.13% in round 12 to 1.08% in round 13;
  • in people aged 64 or younger, the prevalence of infection among those who had received two doses of vaccine was 0.35% compared with 1.15% among those who had not received any vaccine, demonstrating the impact of the vaccination rollout;
  • prevalence is increasing to a lesser extent among those vaccinated, rising from 0.06% in people aged 65 and above who reported receiving two doses in round 12, to 0.24% in the same group in round 13.

Health and Social Care Secretary Sajid Javid said: “As we unlock society and learn to live with COVID-19, we will inevitably see cases rise significantly over coming weeks. But today’s finding show that infection rates are three times lower for those who have had two vaccine doses.

“It is more important than ever to get that life-saving second jab so we can continue to weaken the link between cases, hospitalisations and deaths and build a wall of defence against the virus.

“As we move from regulations to guidance and get back to our everyday lives, see our loved ones and return to work, it is vital people practice good sense and take personal responsibility for their own health and those around them.”

Professor Paul Elliott, director of the REACT programme from Imperial’s School of Public Health, said: “In spite of the successful rollout of the vaccination programme, we are still seeing rapid growth in infections, especially among younger people.

“However, it is encouraging to see lower infection prevalence in people who have had both doses of a vaccine. It is therefore essential that as many people as possible take up both vaccine doses when offered.”